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Merck
CN

SAB5500102

Anti-EZH2 antibody, Rabbit monoclonal

recombinant, expressed in proprietary host, clone SP129, affinity isolated antibody

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
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产品名称

Anti-EZH2 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP129, affinity isolated antibody

biological source

rabbit

recombinant

expressed in proprietary host

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

SP129, monoclonal

species reactivity

human (tested)

species reactivity (predicted by homology)

monkey, frog, mouse, rat

technique(s)

flow cytometry: 1:100
immunoblotting: 1:25
immunohistochemistry: 1:100

isotype

IgG

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... EZH2(2146)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

KMT6/Enhancer of zeste homologue 2 (EZH2) is a histone lysine methyl transferase associated with transcriptional repression. It is a component of the polycomb repressive complexes PRC2 and PRC3. The PRC2 complex catalyses histone H3 K27 trimethylation. EZH2 is ubiquitously expressed during early embryo genesis, and becomes restricted to the central and peripheral nervous systems and sites of fetal hematopoiesis during later development. EZH2 is highly expressed in follicular T-cells and in a variety of tumors such as lymphoma, breast and prostate.

Immunogen

Synthetic peptide corresponding to C-terminus of human EZH2 protein.

Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Ivan Osokine et al.
Cell reports, 38(5), 110329-110329 (2022-02-03)
A little-appreciated feature of early pregnancy is that embryo implantation and placental outgrowth do not evoke wound-healing responses in the decidua, the specialized endometrial tissue that surrounds the conceptus. Here, we provide evidence that this phenomenon is partly due to

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