生物来源
rabbit
质量水平
重组
expressed in proprietary host
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
SP188, monoclonal
种属反应性
human (tested)
技术
flow cytometry: 1:400
immunoblotting: 1:400
immunohistochemistry: 1:100
同位素/亚型
IgG
UniProt登记号
运输
wet ice
储存温度
2-8°C
靶向翻译后修饰
unmodified
基因信息
human ... MAGEA1(4100)
相关类别
一般描述
Melanoma-associated antigen 1 (MAGE-A1) is one of the melanoma associated antigens (MAAs). MAGE-A1 is highly expressed in testis and some human solid tumors such as melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian and renal cell carcinomas.
免疫原
Synthetic peptide derived from the C-terminus of human MAGE-A1 protein.
生化/生理作用
Members of MAGE family play a vital role in maintaining normal cellular physiology. Melanoma-associated antigen 1 (MAGE-A1) serves as a target antigen of patient-derived CD8+ T cells in melanoma. It might be potential target for treating melanoma patients.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
MAGE-F1, a novel ubiquitously expressed member of the MAGE superfamily.
Stone B, et al.
Gene, 267(2), 173-182 (2001)
MAGE-A1 promotes melanoma proliferation and migration through C-JUN activation.
Wang D, et al.
Biochemical and Biophysical Research Communications, 473(4), 959-965 (2016)
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