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Merck
CN

SAB5500139

Sigma-Aldrich

Anti-MAGE-A1 antibody, Rabbit monoclonal

recombinant, expressed in proprietary host, clone SP188, affinity isolated antibody

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UNSPSC代码:
12352203
NACRES:
NA.41
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生物来源

rabbit

质量水平

重组

expressed in proprietary host

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

SP188, monoclonal

种属反应性

human (tested)

技术

flow cytometry: 1:400
immunoblotting: 1:400
immunohistochemistry: 1:100

同位素/亚型

IgG

UniProt登记号

运输

wet ice

储存温度

2-8°C

靶向翻译后修饰

unmodified

基因信息

human ... MAGEA1(4100)

一般描述

Melanoma-associated antigen 1 (MAGE-A1) is one of the melanoma associated antigens (MAAs). MAGE-A1 is highly expressed in testis and some human solid tumors such as melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian and renal cell carcinomas.

免疫原

Synthetic peptide derived from the C-terminus of human MAGE-A1 protein.

生化/生理作用

Members of MAGE family play a vital role in maintaining normal cellular physiology. Melanoma-associated antigen 1 (MAGE-A1) serves as a target antigen of patient-derived CD8+ T cells in melanoma. It might be potential target for treating melanoma patients.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

MAGE-F1, a novel ubiquitously expressed member of the MAGE superfamily.
Stone B, et al.
Gene, 267(2), 173-182 (2001)
MAGE-A1 promotes melanoma proliferation and migration through C-JUN activation.
Wang D, et al.
Biochemical and Biophysical Research Communications, 473(4), 959-965 (2016)

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