SAB5500187
Anti-Thyroid Transcription Factor-1 antibody, Rabbit monoclonal
clone SP141, recombinant, expressed in proprietary host, affinity isolated antibody
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
SP141, monoclonal
Application:
flow cytometry
immunohistochemistry
immunohistochemistry
Species reactivity:
human (tested)
Citations:
1
Technique(s):
flow cytometry: 1:100
immunohistochemistry: 1:100
immunohistochemistry: 1:100
Uniprot accession no.:
产品名称
Anti-Thyroid Transcription Factor-1 antibody, Rabbit monoclonal, clone SP141, recombinant, expressed in proprietary host, affinity isolated antibody
biological source
rabbit
recombinant
expressed in proprietary host
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
SP141, monoclonal
species reactivity
human (tested)
species reactivity (predicted by homology)
rat, mouse
technique(s)
flow cytometry: 1:100
immunohistochemistry: 1:100
isotype
IgG
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NKX2-1(7080)
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Thyroid transcription factor-1 (TTF-1), also known as NK2 homeobox 1(NKX2-1), is a member of the NKx2 family of homeodomain transcription factors. It binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. TTF-1 is expressed in epithelial cells of the thyroid gland and the lung, and their derived tumors such as lung adenocarcinoma and small cell carcinomas and thyroid cancer. It is absent in mesotheliomas, breast cancer, and colon cancer.
Immunogen
Synthetic peptide derived from the internal region of human TTF-1 protein.
Physical form
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
NOTCH4I?L12_16 sensitizes lung adenocarcinomas to EGFR-TKIs through transcriptional down-regulation of HES1.
Zhang, et al.
Nature Communications, 14, 3183-3183 (2023)
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