SAB5600233
Anti-Acetyl-Histone H3 (Lys18) antibody, Rabbit monoclonal
recombinant, expressed in HEK 293 cells, clone RM166, purified immunoglobulin
别名:
H3K18ac, Histone H3 (acetyl K18)
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关于此项目
NACRES:
NA.43
UNSPSC Code:
12352203
Clone:
RM166, monoclonal, recombinant monoclonal
Species reactivity:
vertebrates
Application:
ChIP, ELISA, ICC, IHC, WB, multiplexing
Citations:
1
recombinant
expressed in HEK 293 cells
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
RM166, monoclonal, recombinant monoclonal
form
buffered aqueous glycerol solution
species reactivity
vertebrates
technique(s)
ChIP: 2-10 μg/mL, ELISA: 0.5-2 μg/mL, immunocytochemistry: 0.5-2 μg/mL, immunohistochemistry: 1—10 μg/mL, multiplexing: 0.1-0.5 μg/mL, western blot: 0.5— 2 μg/mL
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
acetylation (Lys18)
Gene Information
human ... H3C1(8350)
Immunogen
An acetyl-peptide corresponding to the Acetyl-Histone H3 (Lys18)
Biochem/physiol Actions
This antibody reacts to Histone H3 acetylated at Lysine 18 (K18ac). No cross reactivity with other acetylated Lysines in histone H3.
Physical form
Solution in phosphate buffered saline containing 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Lactate modulates zygotic genome activation through H3K18 lactylation rather than H3K27 acetylation.
Yanhua Zhao et al.
Cellular and molecular life sciences : CMLS, 81(1), 298-298 (2024-07-12)
In spite of its essential role in culture media, the precise influence of lactate on early mouse embryonic development remains elusive. Previous studies have implicated lactate accumulation in medium affecting histone acetylation. Recent research has underscored lactate-derived histone lactylation as
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