SAB5700277
Anti-Phospho-APP-T668 antibody produced in rabbit
别名:
Aβ42, AAA, ABETA, ABPP, AD1, APP, APPI, Amyloid beta A4, CTFgamma, CVAP, PN-II, PN2, preA4
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关于此项目
NACRES:
NA.43
UNSPSC Code:
12352203
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
rat, mouse
Application:
WB
Citations:
-
biological source
rabbit
Quality Segment
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
34, 72-86
species reactivity
rat, mouse
concentration
0.81 mg/ml
technique(s)
western blot: 1:500-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pThr668)
Gene Information
human ... APP(351)
General description
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
Immunogen
A phospho specific peptide corresponding to residues surrounding T668 of human APP
Physical form
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Preparation Note
Store at -20℃. Avoid freeze / thaw cycles.
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存储类别
12 - Non Combustible Liquids
WGK
WGK 1
闪点 (F)
Not applicable
闪点 (°C)
Not applicable