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SAB5700283

Anti-Phospho-BRAF-S445 antibody produced in rabbit

Name: Anti-Phospho-BRAF-S445 antibody produced in rabbit
Brand: SIGMA

别名:

B-RAF1, B-raf, BRAF, BRAF1, NS7, RAFB1

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关于此项目

NACRES:

NA.43

UNSPSC Code:

12352203

Clone:

polyclonal

Species reactivity:

human, rat

Application:

Citations:

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属性

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

species reactivity

human, rat

concentration

2.22 mg/ml

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

P15056

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer445)

Gene Information

human ... BRAF(673)

说明

General description

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Immunogen

A synthetic phosphorylated peptide around S445 of human BRAF (NP_004324.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c