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Merck
CN

SAB5700315

Sigma-Aldrich

Anti-Phospho-MAP3K7-S412 antibody produced in rabbit

别名:

CSCF, FMD2, MAP3K7, MEKK7, TAK1, TGF1a

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41
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生物来源

rabbit

质量水平

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

53
56
64
67

种属反应性

human

浓度

0.99 mg/ml

技术

western blot: 1:500-1:2000

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

phosphorylation (pSer412)

基因信息

human ... MAP3K7(6885)

一般描述

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

免疫原

A phospho specific peptide corresponding to residues surrounding S412 of human MAP3K7

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

制备说明

Store at -20℃. Avoid freeze / thaw cycles.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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