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Merck
CN

SAB5700315

Anti-Phospho-MAP3K7-S412 antibody produced in rabbit

别名:

CSCF, FMD2, MAP3K7, MEKK7, TAK1, TGF1a

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human
Application:
WB
Citations:
-
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biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

53, 56, 64, 67

species reactivity

human

concentration

0.99 mg/ml

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer412)

Gene Information

human ... MAP3K7(6885)

General description

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Immunogen

A phospho specific peptide corresponding to residues surrounding S412 of human MAP3K7

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品

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分析证书(COA)

Lot/Batch Number

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全球贸易项目编号

货号GTIN
SAB5700315-100UL04065265172608