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SAB5700352

Anti-Phospho-EIF4EBP1-T36 antibody produced in rabbit

Name: Anti-Phospho-EIF4EBP1-T36 antibody produced in rabbit
Brand: SIGMA

别名:

4E-BP1, 4EBP1, BP-1, EIF4EBP1, PHAS-I

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关于此项目

NACRES:

NA.41

UNSPSC Code:

12352203

Clone:

polyclonal

Species reactivity:

human, mouse, rat

Application:

IHC, WB

Citations:

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属性

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

species reactivity

human, mouse, rat

concentration

3.42 mg/ml

technique(s)

immunohistochemistry: 1:50-1:100, western blot: 1:500-1:2000

UniProt accession no.

Q13541

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pThr36)

Gene Information

human ... EIF4EBP1(1978)

说明

General description

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Immunogen

A phospho specific peptide corresponding to residues surrounding T36 of human EIF4EBP1

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c