SAB5700438
Anti-Phospho-POLR2A-S2 antibody produced in rabbit
别名:
POLR2, POLR2A, POLRA, Pol II, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
217
63
species reactivity
rat, human
concentration
1.20 mg/ml
technique(s)
immunofluorescence: 1:50-1:100
immunoprecipitation (IP): 1:50-1:100
western blot: 1:1000-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer2)
Quality Level
Gene Information
human ... POLR2A(5430)
General description
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
Immunogen
A phospho specific peptide corresponding to residues surrounding S2 of human POLR2A
Physical form
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Preparation Note
Store at -20℃. Avoid freeze / thaw cycles.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
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