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SAB5700452

Anti-Phospho-ACLY-S455 antibody produced in rabbit

Name: Anti-Phospho-ACLY-S455 antibody produced in rabbit
Brand: SIGMA

别名:

ACL, ACLY, ATPCL, CLATP

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关于此项目

NACRES:

NA.41

UNSPSC Code:

12352203

Clone:

polyclonal

Species reactivity:

rat, mouse, human

Application:

IHC, IP, WB

Citations:

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属性

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

119, 120, 91

species reactivity

rat, mouse, human

concentration

1.15 mg/ml

technique(s)

immunohistochemistry: 1:50-1:100, immunoprecipitation (IP): 1:50-1:100, western blot: 1:500-1:2000

UniProt accession no.

P53396

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer455)

Gene Information

human ... ACLY(47)

说明

General description

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Immunogen

A synthetic phosphorylated peptide around S455 of human ACLY (NP_001087.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c