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Merck
CN

SAB5700521

Anti-Phospho-PERK-T982 antibody produced in rabbit

别名:

EIF2AK3, PEK, PERK, WRS

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
mouse, human, rat
Application:
WB
Citations:
-
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biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

125

species reactivity

mouse, human, rat

concentration

1.67 mg/ml

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pThr982)

Gene Information

human ... EIF2AK3(9451)

General description

The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

Immunogen

A phospho specific peptide corresponding to residues surrounding T980 of human PERK.

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
低风险生物材料

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历史批次信息供参考:

分析证书(COA)

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全球贸易项目编号

货号GTIN
SAB5700521-100UL04065265176668