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NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human, rat, mouse
Application:
immunohistochemistry
western blot
western blot
Technique(s):
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
western blot: 1:500-1:2000
Citations:
Uniprot accession no.:
biological source
rabbit
antibody product type
primary antibodies
clone
polyclonal
form
liquid
species reactivity
human, rat, mouse
concentration
0.976 mg/mL
technique(s)
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pTyr693)
Quality Level
Gene Information
human ... STAT4(6775)
General description
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
Immunogen
A phospho specific peptide corresponding to residues surrounding Y693 of human STAT4
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
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