biological source
rabbit
Quality Segment
antibody product type
primary antibodies
clone
polyclonal
form
liquid
species reactivity
mouse, human, rat
concentration
0.429 mg/mL
technique(s)
western blot: 1:500-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer1490)
Gene Information
human ... LRP6(4040)
General description
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
Immunogen
A synthetic phosphorylated peptide around S1490 of human LRP6.
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Still not finding the right product?
试用我们的 产品选型工具 工具缩小选择范围
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB5701936-100UL | 04065267679136 |