SAB5702037
Anti-IDO1 Antibody, clone 6W2F7, Rabbit Monoclonal
别名:
IDO, IDO-1, INDO
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关于此项目
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
6W2F7, monoclonal
Application:
IHC, WB
Citations:
-
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
6W2F7, monoclonal
form
liquid
mol wt
42 kDa
Quality Level
Gene Information
human ... IDO1(3620)
concentration
0.48 mg/mL
technique(s)
immunohistochemistry: 1:50 - 1:200, western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
IESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDV
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IDO1 (P14902).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IHC
存储类别
10 - Combustible liquids
wgk
WGK 1
法规信息
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