SAB5702059
Anti-HSPB8/HSP22 Antibody, clone 3K10W1, Rabbit Monoclonal
别名:
CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
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NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
3K10W1, monoclonal
Application:
immunofluorescence
western blot
western blot
Species reactivity:
rat, rat, human
Citations:
Technique(s):
immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:2000
western blot: 1:500 - 1:2000
Uniprot accession no.:
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
3K10W1, monoclonal
form
liquid
mol wt
22 kDa
species reactivity
rat, rat, human
concentration
0.50 mg/mL
technique(s)
immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
MADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAWPGTLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCV
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... HSPB8(26353)
Application
WB, IF/ICC
General description
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HSPB8/HSP22 (Q9UJY1).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
存储类别
10 - Combustible liquids
wgk
WGK 1
法规信息
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