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About This Item

UNSPSC代码:
12352203
NACRES:
NA.46
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生物来源

rabbit

质量水平

偶联物

unconjugated

物料

colorless

克隆

6I0O4, monoclonal

表单

liquid

分子量

140 kDa

种属反应性

human, rat, rat

浓度

0.5 mg/mL

技术

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

颜色

colorless

同位素/亚型

IgG

免疫原序列

EEQGLINSSVTKCFSSKNSPLKDSFSNSSWEIEAQAFFILSDQHPNIISPHLTFSEGLDELLKLEGNFPEENNDKKSIYYLGVTSIKKRESGVLLTDKSRV

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... LEPR(3953)

一般描述

The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1000-1100 of human Leptin Receptor (P48357).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

应用

WB, IHC

储存分类代码

10 - Combustible liquids

WGK

WGK 1


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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