biological source
rabbit
conjugate
unconjugated
material
colorless
clone
5E0D2, monoclonal
form
liquid
mol wt
160 kDa
species reactivity
human
concentration
0.58 mg/mL
technique(s)
immunofluorescence: 1:50 - 1:200, western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGE
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NEFM(4741)
General description
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human Neurofilament M (P07197).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IF/ICC
存储类别
10 - Combustible liquids
wgk
WGK 1
法规信息
常规特殊物品
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