This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]

A synthetic peptide corresponding to a sequence within amino acids 690-789 of human TRAF6BP/TAX1BP1 (Q86VP1).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

WB