[KO Validated]Anti-SUMO1 Antibody, clone 6F8B6, Rabbit Monoclonal

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]

A synthetic peptide corresponding to a sequence within amino acids 1-101 of human Sumo 1 (P63165).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

WB, IHC, IF/ICC