产品名称
Anti-α-Synuclein Antibody, clone 10Y4X3, Rabbit Monoclonal,
生物来源
rabbit
质量水平
物料
colorless
克隆
10Y4X3, monoclonal
表单
liquid
分子量
18 kDa
种属反应性
rat, rat, human
浓度
1mg/mL
技术
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:1000
颜色
colorless
同位素/亚型
IgG
免疫原序列
TKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... SNCA(6622)
一般描述
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer′s disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
免疫原
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 59-140 of human alpha-Synuclein (NP_000336.1).
应用
WB, IHC
警示用语：
Warning
危险声明
危险分类
Aquatic Chronic 2 - Skin Sens. 1
储存分类代码
10 - Combustible liquids
WGK
WGK 3
法规信息
常规特殊物品
此项目有
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持