SAB5702273
Anti-Ret Antibody, clone 3U8T6, Rabbit Monoclonal
别名:
RET,CDHF12,CDHR16,HSCR1,MEN2A,MEN2B,MTC1,PTC,RET-ELE1,RET51
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关于此项目
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
3U8T6, monoclonal
Application:
immunofluorescence
western blot
western blot
Species reactivity:
human, rat, rat
Citations:
Technique(s):
immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:1000
western blot: 1:500 - 1:1000
Uniprot accession no.:
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
3U8T6, monoclonal
form
liquid
species reactivity
human, rat, rat
concentration
1.00 mg/mL
technique(s)
immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:1000
color
colorless
isotype
IgG
immunogen sequence
DISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRYPNDSVYANWM
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... Ret(5979)
Application
WB, IF/ICC
General description
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1000-1100 of human Ret (NP_066124.1).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Skin Sens. 1
存储类别
10 - Combustible liquids
wgk
WGK 3
法规信息
常规特殊物品
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