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Merck
CN

SAB5702282

Anti-SOCS1 Antibody, clone 5T6Z10, Rabbit Monoclonal

别名:

SOCS1,CIS1,CISH1,JAB,SOCS-1,SSI-1,SSI1,TIP3,TIP-3

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关于此项目

NACRES:
NA.46
UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

material

colorless

clone

5T6Z10, monoclonal

form

liquid

species reactivity

rat, human, rat

concentration

1 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200
immunohistochemistry: 1:50 - 1:200

color

colorless

isotype

IgG

immunogen sequence

MVAHNQVAADNAVSTAAEPRRRPEPSSSSSSSPAAPARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRAEPVGT

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... SOCS1(8651)

Application

IHC, IF/ICC

General description

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SOCS1 (NP_003736.1).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

pictograms

Exclamation markEnvironment

signalword

Warning

hcodes

Hazard Classifications

Aquatic Chronic 2 - Skin Sens. 1

存储类别

10 - Combustible liquids

wgk

WGK 3

法规信息

常规特殊物品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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