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Merck
CN

SAB5702328

Sigma-Aldrich

Anti-TNNC1 Antibody, clone 8Z4V9, Rabbit Monoclonal

别名:

CMD1Z, CMH13, TN-C, TNC, TNNC

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.46
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生物来源

rabbit

质量水平

偶联物

unconjugated

物料

colorless

克隆

8Z4V9, monoclonal

表单

liquid

分子量

18 kDa

种属反应性

mouse, rat

浓度

0.33 mg/mL

技术

western blot: 1:500 - 1:2000

颜色

colorless

同位素/亚型

IgG

免疫原序列

MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDL

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... TNNC1(7134)

一般描述

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TNNC1 (P63316).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

应用

WB

储存分类代码

10 - Combustible liquids

WGK

WGK 1


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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