SAB5702352
Anti-Filamin A Antibody, clone 3X8Y9, Rabbit Monoclonal
别名:
ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD
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NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
rat, human
Conjugate:
unconjugated
Application:
IHC, WB
Citations:
-
biological source
rabbit
Quality Segment
conjugate
unconjugated
material
colorless
clone
3X8Y9, monoclonal
form
liquid
mol wt
280 kDa
species reactivity
rat, human
concentration
0.25 mg/mL
technique(s)
immunohistochemistry: 1:50 - 1:200, western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
GAPGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVVP
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... FLNA(2316)
General description
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 2548-2647 of human Filamin A (P21333).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IHC
存储类别
10 - Combustible liquids
wgk
WGK 1