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Merck
CN

SAB5702404

Anti-BMP15 Antibody, clone 6K5C3, Rabbit Monoclonal

别名:

GDF9B, ODG2, POF4

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关于此项目

NACRES:
NA.46
UNSPSC Code:
12352203
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isotype

IgG

biological source

rabbit

conjugate

unconjugated

material

colorless

clone

6K5C3, monoclonal

form

liquid

mol wt

50 kDa

species reactivity

rat, human, rat

concentration

0.31 mg/mL

technique(s)

western blot: 1:500 - 1:2000

color

colorless

immunogen sequence

LHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNLINQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... BMP15(9210)

Application

WB

General description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. [provided by RefSeq, Aug 2016]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 293-392 of human BMP15 (O95972).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

存储类别

10 - Combustible liquids

wgk

WGK 1

法规信息

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