SAB5702444
Anti-Rad50 Antibody, clone 5M2K10, Rabbit Monoclonal
别名:
NBSLD, RAD502, hRad50
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关于此项目
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
5M2K10, monoclonal
Application:
immunoprecipitation (IP)
western blot
western blot
Species reactivity:
rat, human, rat
Citations:
Technique(s):
immunoprecipitation (IP): 1:50 - 1:200
western blot: 1:500 - 1:2000
western blot: 1:500 - 1:2000
Uniprot accession no.:
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
5M2K10, monoclonal
form
liquid
mol wt
154 kDa
species reactivity
rat, human, rat
concentration
0.85 mg/mL
technique(s)
immunoprecipitation (IP): 1:50 - 1:200
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
RCSAGQKVLASLIIRLALAETFCLNCGIIALDEPTTNLDRENIESLAHALVEIIKSRSQQRNFQLLVITHDEDFVELLGRSEYVEKFYRIKKNIDQCSEIV
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... RAD50(10111)
Application
WB,IP
General description
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1200-1300 of human Rad50 (Q92878).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
存储类别
10 - Combustible liquids
wgk
WGK 1
法规信息
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