Anti-PARP2 Antibody, clone 6G5U7, Rabbit Monoclonal

This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008]

A synthetic peptide corresponding to a sequence within amino acids 484-583 of human PARP2 (Q9UGN5).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

WB