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Merck
CN

SAB5702692

Anti-JARID2 Antibody, clone 3L5C5, Rabbit Monoclonal

别名:

JMJ

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关于此项目

NACRES:
NA.46
UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

material

colorless

clone

3L5C5, monoclonal

form

liquid

mol wt

150 kDa

species reactivity

human, rat, rat

concentration

0.7mg/mL

technique(s)

western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

FEEGPSRKRPRLQAQRKFAQSQPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQDEEEVEEEDDETEDVKTATN

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... JARID2(3720)

Application

WB

General description

This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human JARID2 (Q92833).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

存储类别

10 - Combustible liquids

wgk

WGK 1

法规信息

常规特殊物品
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分析证书(COA)

Lot/Batch Number

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