生物来源
rabbit
质量水平
偶联物
unconjugated
物料
colorless
克隆
4A3G9, monoclonal
表单
liquid
分子量
146 kDa
种属反应性
rat, rat, human
浓度
0.27 mg/mL
技术
immunofluorescence: 1:50 - 1:200
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000
颜色
colorless
同位素/亚型
IgG
免疫原序列
MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQ
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... SF3B1(23451)
一般描述
This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
免疫原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SF3B1 (O75533).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
应用
WB, IHC, IF/ICC
储存分类代码
10 - Combustible liquids
WGK
WGK 1
法规信息
常规特殊物品
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