Anti-ITPA Antibody, clone 2O6K5, Rabbit Monoclonal

This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.

A synthetic peptide corresponding to a sequence within amino acids 70-150 of human ITPA (Q9BY32).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

WB