SAB6010029
Anti-Histone H3.3 antibody, clone 4H2, Rabbit Monoclonal
recombinant, expressed in HEK293F cells
别名:
Histone H3.3, H3F3A, H3.3A, H3F3, PP781, AND, H3F3B, H3.3B
重组
expressed in HEK 293 F cells
质量水平
偶联物
unconjugated
抗体产品类型
primary antibodies
克隆
4H2, recombinant monoclonal
表单
liquid
分子量
150 kDa
纯化方式
affinity chromatography
种属反应性
human
浓度
2mg/ml
技术
ELISA: 2000:10000
flow cytometry: 1:50-1:200
immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200
同位素/亚型
IgG
UniProt登记号
运输
wet ice
储存温度
-10 to -25°C
靶向翻译后修饰
unmodified
一般描述
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
免疫原
A synthesized peptide derived from human Histone H3.3
外形
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
制备说明
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
其他说明
70-100aa
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
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