SAB6010050
Anti-phospho-FOXO3 (S253) antibody, clone 1E1, Rabbit Monoclonal
recombinant, expressed in HEK293F cells
别名:
Forkhead box protein O3, AF6q21 protein, FOXO3
重组
expressed in HEK 293 F cells
质量水平
偶联物
unconjugated
抗体产品类型
primary antibodies
克隆
1E1, recombinant monoclonal
表单
liquid
分子量
150 kDa
纯化方式
affinity chromatography
种属反应性
human
浓度
0.8mg/ml
技术
ELISA: 2000:10000
flow cytometry: 1:50-1:200
immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200
同位素/亚型
IgG
UniProt登记号
运输
wet ice
储存温度
-10 to -25°C
靶向翻译后修饰
phosphorylation (pSer253)
一般描述
Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5′-[AG]TAAA[TC]A-3′. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3′UTR of MYC transcript and prevent its translation.
免疫原
A synthesized peptide derived from human Phospho-FOXO3 (S253)
外形
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
制备说明
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
其他说明
AV-pS-MD
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
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