产品名称
Anti Dual specificity phosphatase 1 Antibody, clone 23GB5760, Rabbit Monoclonal, clone 23GB5760, recombinant rabbit monoclonal, expressed in HEK293 cells
biological source
rabbit (Monoclonal)
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
23GB5760, recombinant monoclonal
form
buffered aqueous glycerol solution
mol wt
39 kDa
species reactivity
human, rat
packaging
vial of 1.5 mL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
Quality Level
Gene Information
human ... DUSP1(1843)
sustainability
Greener Alternative Product
concentration
1.5 mg/ml
technique(s)
flow cytometry: 1:2000
western blot: 1:1,000-1:5,000
isotype
IgG
Ensembl | human accession no.
NCBI accession no.
UniProt accession no.
greener alternative category
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy. [provided by RefSeq, Aug 2017]
We are committed to bringing you Greener Alternative Products. This product is a Design for Sustainability (DfS) developed product, which belongs to one of the four categories of greener alternatives. Click here to view its DfS scorecard.
Immunogen
A synthesized peptide corresponding to a sequence within amino acids 102-150 of human DUSP1 [NP_004408.1].
Other Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Physical form
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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