产品名称
Anti-phospho-LAT (Tyr220) Antibody, clone 24GB1375, Rabbit Monoclonal, clone 24GB1375, recombinant rabbit monoclonal, expressed in HEK293 cells
biological source
rabbit (Monoclonal)
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
24GB1375, recombinant monoclonal
form
buffered aqueous glycerol solution
mol wt
28 kDa
species reactivity
human, rat
packaging
vial of 1.5 mL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
Quality Level
Gene Information
human ... LAT(27040)
sustainability
Greener Alternative Product
concentration
2.35 mg/ml
technique(s)
western blot: 1:1,000-1:5,000
isotype
IgG
Ensembl | human accession no.
NCBI accession no.
UniProt accession no.
greener alternative category
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Physical form
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
General description
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
We are committed to bringing you Greener Alternative Products. This product is a Design for Sustainability (DfS) developed product, which belongs to one of the four categories of greener alternatives. Click here to view its DfS scorecard.
Immunogen
A synthesized peptide corresponding to a sequence within amino acids 184-198 of human Phospho-LAT (Y220) [NP_055202.1].
Other Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
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