生物来源
rabbit (Monoclonal)
质量水平
重组
expressed in HEK 293 cells
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
24GB2230, recombinant monoclonal
表单
buffered aqueous glycerol solution
分子量
34 kDa
种属反应性
human, rat
包装
vial of 1.5 mL
增强验证
recombinant expression
Learn more about Antibody Enhanced Validation
浓度
0.8 mg/ml
技术
flow cytometry: 1:2000
western blot: 1:1,000-1:5,000
同位素/亚型
IgG
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运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... TRADD(8717)
一般描述
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]
免疫原
A synthesized peptide corresponding to a sequence within amino acids 210-312 of human TRADD [NP_003780.1].
外形
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
其他说明
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
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