SAB6012196
Anti UBA7 Antibody, clone 24GB2660, Rabbit Monoclonal
clone 24GB2660, recombinant rabbit monoclonal, expressed in HEK293 cells
别名:
UBA1B, UBE1L, UBE2, UBE7
生物来源
rabbit (Monoclonal)
质量水平
重组
expressed in HEK 293 cells
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
24GB2660, recombinant monoclonal
表单
buffered aqueous glycerol solution
分子量
112 kDa
种属反应性
human, rat
包装
vial of 1.5 mL
增强验证
recombinant expression
Learn more about Antibody Enhanced Validation
浓度
0.25 mg/ml
技术
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
同位素/亚型
IgG
基因组数据库 |人类登记号
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... UBA7(7318)
一般描述
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008]
免疫原
A synthesized peptide corresponding to a sequence within amino acids 1-62 of human Ube1L / UBA7 [NP_003326.2].
外形
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
其他说明
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
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