SAB6012218
Anti DNA methyltransferase 3 alpha Antibody, clone 23GB2230, Rabbit Monoclonal
clone 23GB2230, recombinant rabbit monoclonal, expressed in HEK293 cells
别名:
DNMT3A2, Dnmt3a, HESJAS, TBRS
生物来源
rabbit (Monoclonal)
质量水平
重组
expressed in HEK 293 cells
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
23GB2230, recombinant monoclonal
表单
buffered aqueous glycerol solution
分子量
102 kDa
种属反应性
human, rat
包装
vial of 1.5 mL
增强验证
recombinant expression
Learn more about Antibody Enhanced Validation
浓度
0.5 mg/ml
技术
flow cytometry: 1:2000
western blot: 1:1,000-1:5,000
同位素/亚型
IgG
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NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... DNMT3A(1788)
一般描述
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]
免疫原
A synthesized peptide corresponding to a sequence within amino acids 609-624 of human Dnmt3a [NP_072046.2].
外形
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
其他说明
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
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