SAB6012287
KD-Validated Anti CHMP2B Antibody, clone 23GB3070, Rabbit Monoclonal
clone 23GB3070, recombinant rabbit monoclonal, expressed in HEK293 cells
别名:
ALS17, CHMP2.5, CHMP2b, DMT1, VPS2B
产品名称
KD-Validated Anti CHMP2B Antibody, clone 23GB3070, Rabbit Monoclonal, clone 23GB3070, recombinant rabbit monoclonal, expressed in HEK293 cells
biological source
rabbit (Monoclonal)
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
23GB3070, recombinant monoclonal
form
buffered aqueous glycerol solution
mol wt
24 kDa
species reactivity
human, rat
packaging
vial of 1.5 mL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
Quality Level
Gene Information
human ... CHMP2B(25978)
sustainability
Greener Alternative Product
concentration
0.4 mg/ml
technique(s)
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
isotype
IgG
Ensembl | human accession no.
NCBI accession no.
UniProt accession no.
greener alternative category
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. [provided by RefSeq, Jul 2008]
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Immunogen
A synthesized peptide corresponding to a sequence within amino acids 171-213 of CHMP2B [NP_054762.2].
Other Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Physical form
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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