KD-Validated Anti HNRNPM Antibody, clone 23GB4895, Rabbit Monoclonal

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

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A synthesized peptide corresponding to a sequence within amino acids 250-300 of human HNRNPM [NP_005959.2].

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.