SAB6012381
KD-Validated Anti HuR / ELAVL1 Antibody, clone 23GB5815, Rabbit Monoclonal
clone 23GB5815, recombinant rabbit monoclonal, expressed in HEK293 cells
别名:
HUA, HUR, MELG
生物来源
rabbit (Monoclonal)
质量水平
重组
expressed in HEK 293 cells
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
23GB5815, recombinant monoclonal
表单
buffered aqueous glycerol solution
分子量
36 kDa
种属反应性
rat, human
包装
vial of 1.5 mL
增强验证
recombinant expression
Learn more about Antibody Enhanced Validation
浓度
0.8 mg/ml
技术
flow cytometry: 1:2000
western blot: 1:1,000-1:5,000
同位素/亚型
IgG
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NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... ELAVL1(1994)
一般描述
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3′ untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]
免疫原
A synthesized peptide corresponding to a sequence within amino acids 52-96 of human HuR / ELAVL1 [NP_001410.2].
外形
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
其他说明
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
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