SAB6012382
KD-Validated Anti GEMIN2 Antibody, clone 23GB5835, Rabbit Monoclonal
clone 23GB5835, recombinant rabbit monoclonal, expressed in HEK293 cells
别名:
Gemin-2, SIP1
生物来源
rabbit (Monoclonal)
质量水平
重组
expressed in HEK 293 cells
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
23GB5835, recombinant monoclonal
表单
buffered aqueous glycerol solution
分子量
32 kDa
种属反应性
rat, human
包装
vial of 1.5 mL
增强验证
recombinant expression
Learn more about Antibody Enhanced Validation
浓度
0.5 mg/ml
技术
flow cytometry: 1:2000
western blot: 1:1,000-1:5,000
同位素/亚型
IgG
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NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... GEMIN2(8487)
一般描述
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011]
免疫原
A synthesized peptide corresponding to a sequence within amino acids 11-71 of human Gemin 2 [NP_001009182.1].
外形
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
其他说明
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
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