SAB6012394
KD-Validated Anti Farnesyl diphosphate synthase Antibody, clone 23GB1395, Rabbit Monoclonal
clone 23GB1395, recombinant rabbit monoclonal, expressed in HEK293 cells
别名:
FPPS, FPS, POROK9
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关于此项目
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
23GB1395, recombinant monoclonal
Application:
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Species reactivity:
human
Citations:
Technique(s):
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
Uniprot accession no.:
产品名称
KD-Validated Anti Farnesyl diphosphate synthase Antibody, clone 23GB1395, Rabbit Monoclonal, clone 23GB1395, recombinant rabbit monoclonal, expressed in HEK293 cells
biological source
rabbit (Monoclonal)
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
23GB1395, recombinant monoclonal
form
buffered aqueous glycerol solution
mol wt
48 kDa
species reactivity
human
packaging
vial of 1.5 mL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
Quality Level
Gene Information
human ... FDPS(2224)
sustainability
Greener Alternative Product
concentration
0.6 mg/ml
technique(s)
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
isotype
IgG
Ensembl | human accession no.
NCBI accession no.
UniProt accession no.
greener alternative category
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]
We are committed to bringing you Greener Alternative Products. This product is a Design for Sustainability (DfS) developed product, which belongs to one of the four categories of greener alternatives. Click here to view its DfS scorecard.
Immunogen
A synthesized peptide corresponding to a sequence within amino acids 370-410 of human FDPS [NP_001129293.1].
Other Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Physical form
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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