SAB6012456
KD-Validated Anti Ubiquitin Specific Peptidase 5 Antibody, clone 24GB2480, Rabbit Monoclonal
clone 24GB2480, recombinant rabbit monoclonal, expressed in HEK293 cells
别名:
IsoT
生物来源
rabbit (Monoclonal)
质量水平
重组
expressed in HEK 293 cells
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
24GB2480, recombinant monoclonal
表单
buffered aqueous glycerol solution
分子量
96 kDa
种属反应性
rat, human
包装
vial of 1.5 mL
增强验证
recombinant expression
Learn more about Antibody Enhanced Validation
浓度
1 mg/ml
技术
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
同位素/亚型
IgG
基因组数据库 |人类登记号
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... USP5(8078)
一般描述
Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010]
免疫原
A synthesized peptide corresponding to a sequence within amino acids 770-835 of human USP5 [NP_001092006.1].
外形
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
其他说明
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
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