SAB6012457
KD-Validated Anti Uracil DNA Glycosylase Antibody, clone 24GB2530, Rabbit Monoclonal
clone 24GB2530, recombinant rabbit monoclonal, expressed in HEK293 cells
别名:
DGU, HIGM4, UDG, UNG1, UNG2
生物来源
rabbit (Monoclonal)
质量水平
重组
expressed in HEK 293 cells
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
24GB2530, recombinant monoclonal
表单
buffered aqueous glycerol solution
分子量
35 kDa
种属反应性
human
包装
vial of 1.5 mL
增强验证
recombinant expression
Learn more about Antibody Enhanced Validation
浓度
0.705 mg/ml
技术
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
同位素/亚型
IgG
基因组数据库 |人类登记号
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... UNG(7374)
一般描述
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010]
免疫原
A synthesized peptide corresponding to a sequence within amino acids 20-88 of human UNG [NP_550433.1].
外形
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
其他说明
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
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