SAB6012468
KD-Validated Anti Chromodomain helicase DNA binding protein 3 Antibody, clone 23GB1380, Rabbit Monoclonal
clone 23GB1380, recombinant rabbit monoclonal, expressed in HEK293 cells
别名:
HZFH, MI-2A, SNIBCPS, ZFH
产品名称
KD-Validated Anti Chromodomain helicase DNA binding protein 3 Antibody, clone 23GB1380, Rabbit Monoclonal, clone 23GB1380, recombinant rabbit monoclonal, expressed in HEK293 cells
biological source
rabbit (Monoclonal)
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
23GB1380, recombinant monoclonal
form
buffered aqueous glycerol solution
mol wt
226 kDa
species reactivity
rat, human
packaging
vial of 1.5 mL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
Quality Level
Gene Information
human ... CHD3(1107)
sustainability
Greener Alternative Product
concentration
2.5 mg/ml
technique(s)
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
isotype
IgG
Ensembl | human accession no.
NCBI accession no.
UniProt accession no.
greener alternative category
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Other Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Physical form
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
General description
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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Immunogen
A synthesized peptide corresponding to a sequence within amino acids 1940-2000 of human CHD3 [NP_001005273.1].
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