SAB6012469
KD-Validated Anti Chromodomain helicase DNA binding protein 3 Antibody, clone 23GB1305, Rabbit Monoclonal
clone 23GB1305, recombinant rabbit monoclonal, expressed in HEK293 cells
别名:
HZFH, MI-2A, SNIBCPS, ZFH
生物来源
rabbit (Monoclonal)
质量水平
重组
expressed in HEK 293 cells
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
23GB1305, recombinant monoclonal
表单
buffered aqueous glycerol solution
分子量
226 kDa
种属反应性
rat, human
包装
vial of 1.5 mL
增强验证
recombinant expression
Learn more about Antibody Enhanced Validation
浓度
1.25 mg/ml
技术
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
同位素/亚型
IgG
基因组数据库 |人类登记号
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... CHD3(1107)
一般描述
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
免疫原
A synthesized peptide corresponding to a sequence within amino acids 220-300 of human CHD3 [NP_001005273.1].
外形
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
其他说明
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
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