SAB6012492
KD-Validated Anti NF2 / Merlin Antibody, clone 23GB2620, Rabbit Monoclonal
clone 23GB2620, recombinant rabbit monoclonal, expressed in HEK293 cells
别名:
BANF, MERLIN, SCH, SWNV
产品名称
KD-Validated Anti NF2 / Merlin Antibody, clone 23GB2620, Rabbit Monoclonal, clone 23GB2620, recombinant rabbit monoclonal, expressed in HEK293 cells
biological source
rabbit (Monoclonal)
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
23GB2620, recombinant monoclonal
form
buffered aqueous glycerol solution
mol wt
70 kDa
species reactivity
rat, human
packaging
vial of 1.5 mL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
Quality Level
Gene Information
human ... NF2(4771)
sustainability
Greener Alternative Product
concentration
0.35 mg/ml
technique(s)
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
isotype
IgG
Ensembl | human accession no.
NCBI accession no.
UniProt accession no.
greener alternative category
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that link cytoskeletal components with proteins in the cell membrane. The encoded protein is involved in regulation of contact-dependent inhibition of cell proliferation and functions in cell-cell adhesion and transmembrane signaling. The encoded protein has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics, and proteins involved in regulating ion transport. Disruption of this protein′s function has been implicated in tumorigenesis and metastasis. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. [provided by RefSeq, May 2022]
We are committed to bringing you Greener Alternative Products. This product is a Design for Sustainability (DfS) developed product, which belongs to one of the four categories of greener alternatives. Click here to view its DfS scorecard.
Immunogen
A synthesized peptide corresponding to a sequence within amino acids 550-595 of human NF2 / Merlin [NP_000259.1].
Other Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Physical form
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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