form
powder
color
white
storage temp.
room temp
SMILES string
[I-].[N+]21([C@H](CC([C@H](C2)C=C)CC1)[C@@H](O)c3c4c(ncc3)ccc(c4)OC)C
InChI
1S/C21H27N2O2.HI/c1-4-14-13-23(2)10-8-15(14)11-20(23)21(24)17-7-9-22-19-6-5-16(25-3)12-18(17)19;/h4-7,9,12,14-15,20-21,24H,1,8,10-11,13H2,2-3H3;1H/q+1;/p-1/t14-,15?,20+,21-,23?;/m0./s1
InChI key
AJQSDVGBERUTGX-QVEQJUGRSA-M
Application
NMQ/N-methyl-quinidine - MDR1/P-gp substrate has been used as a probe substrate for multidrug resistance protein 1 (MDR1) in vesicles assay.
Biochem/physiol Actions
SOLVO Biotechnology offers NMQ as a selective substrate for the MDR1 membrane transporter.
NMQ was shown to be actively transported by human MDR1/P-gp and rat Mdr1b efflux transporters.
NMQ was shown to be actively transported by human MDR1/P-gp and rat Mdr1b efflux transporters.
