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Merck
CN

SBR00059

Sigma-Aldrich

Balofloxacin

≥98% (HPLC), powder

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关于此项目

线性分子式:
C20H24FN3O4.2H2O
化学文摘社编号:
UNSPSC代码:
51101500
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质量水平

方案

≥98% (HPLC)

表单

powder

颜色

off-white

抗生素抗菌谱

(anaerobic bacteria)
Gram-negative bacteria
Gram-positive bacteria

作用机制

DNA synthesis | inhibits

SMILES字符串

CNC1CCCN(C1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F

InChI

1S/C20H24FN3O4/c1-22-11-4-3-7-23(9-11)17-15(21)8-13-16(19(17)28-2)24(12-5-6-12)10-14(18(13)25)20(26)27/h8,10-12,22H,3-7,9H2,1-2H3,(H,26,27)

InChI key

MGQLHRYJBWGORO-UHFFFAOYSA-N

一般描述

Balofloxacin is a broad spectrum synthetic fluoroquinolone antibiotic. It exerts its antibacterial activity by inhibiting DNA gyrase and topoisomerase IV, which are enzymes essential for bacterial DNA synthesis and replication.

应用

One of the main applications of fluoroquinolones like Balofloxacin is their ability to target and inhibit bacterial DNA gyrase and topoisomerase IV, which are enzymes that are essential for bacterial DNA replication and transcription. Because of their potency against these targets, fluoroquinolones have been used as lead compounds for the development of new antibiotics and other drugs that target these enzymes.

生化/生理作用

Balofloxacin inhibits bacterial DNA synthesis by interfering with the activity of DNA gyrase and topoisomerase IV enzymes, which are necessary for the replication, transcription, and repair of bacterial DNA. Balofloxacin is active against gram-negative, gram-positive, and anaerobic bacteria.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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