质量水平
方案
≥97% (HPLC)
表单
powder
颜色
white to off-white
抗生素抗菌谱
mycobacteria
作用机制
enzyme | inhibits
SMILES字符串
CN(C)CC[C@@](C1=CC=CC2=CC=CC=C21)([C@H](C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O.C(=C/C(=O)O)\C(=O)O
InChI
1S/C32H31BrN2O2.C4H4O4/c1-35(2)19-18-32(36,28-15-9-13-22-10-7-8-14-26(22)28)30(23-11-5-4-6-12-23)27-21-24-20-25(33)16-17-29(24)34-31(27)37-3;5-3(6)1-2-4(7)8/h4-17,20-21,30,36H,18-19H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t30-,32-;/m1./s1
InChI key
ZLVSPMRFRHMMOY-WWCCMVHESA-N
一般描述
Bedaquiline fumarate is an antibioitc with antimycobacterial properties. Bedaquiline fumarate a fumarate salt prepared from equimolar amounts of bedaquiline and fumaric acid. It has a role as an antitubercular agent and an ATP synthase inhibitor.
应用
Bedaquiline Fumarate has also been studied for its potential use in bioluminescence imaging, due to its ability to bind to a reporter protein and enhance its luminescence signal. This has potential applications in a variety of biological research areas, such as protein-protein interactions, drug discovery, and disease modeling.
生化/生理作用
Bedaquiline Fumarate is an antimycobacterial agent that inhibits mycobacterial ATP synthase, an enzyme essential for energy metabolism in Mycobacterium tuberculosis. Inhibition of ATP synthase disrupts the energy production of the bacteria and leads to their death. Bedaquiline Fumarate is active against mycobacteria.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Aquatic Chronic 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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